HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
5-(4-Amino-3-fluorophenoxy)-N-methylnicotinamide → 5-(4-Aminophenoxy)-N-methylnicotinamide
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 5-(4-Amino-3-fluorophenoxy)-N-methylnicotinamide | HCID 58385422 | — |
| Edukt | 5-(4-Amino-3-fluorophenoxy)nicotinic acid methyl ester | HCID 59987503 | — |
| Produkt | 5-(4-Aminophenoxy)-N-methylnicotinamide | HCID 58385382 | — |
Reaktionsschritte
The title compound was prepared in the same manner described for 5-(4-amino-3-fluorophenoxy)-N-methylnicotinamide, substituting 5-(4-aminophenoxy)nicotinic acid methyl ester for 5-(4-amino-3-fluorophenoxy)nicotinic acid methyl ester. 1H NMR (DMSO-d6) δ 8.65 (m, 2H), 8.40 (d, J=2.7 Hz, 1H), 7.52 (t, J=2.2 Hz, 1H), 6.84 (d, J=8.7 Hz, 2H), 6.62 (d, J=8.7 Hz, 2H), 5.01 (s, 2H), 2.75 (d, J=4.4 Hz, 3H); MS LC-MS [M+H]+=244.2, RT=0.29 min.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08076488B2 |
| Quelldatensatz | uspto-grants-2011_12 |
| ORD ID | ord-6a9bc59412df4210bef5b7dff7a87aea |
| Quellennotiz | uspto-grants-2011_12 |