HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
5-(4-Amino-3-fluorophenoxy)-N-methylnicotinamide → 5-(4-Amino-2-fluorophenoxy)-N-methylnicotinamide
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 5-(4-Amino-3-fluorophenoxy)-N-methylnicotinamide | HCID 58385422 | — |
| Edukt | 5-(4-Amino-3-fluorophenoxy)nicotinic acid methyl ester | HCID 59987503 | — |
| Produkt | 5-(4-Amino-2-fluorophenoxy)-N-methylnicotinamide | HCID 58385406 | — |
Reaktionsschritte
The title compound was prepared in the same manner described for 5-(4-amino-3-fluorophenoxy)-N-methylnicotinamide, substituting 5-(4-amino-2-fluorophenoxy)-nicotinic acid methyl ester for 5-(4-amino-3-fluorophenoxy)nicotinic acid methyl ester. 1H NMR (DMSO-d6) 67.80 (d, J=1.8 Hz, 1H), 7.53 (d, J=2.7 Hz, 1H), 6.83 to 6.81 (m, 1H), 6.15 (t, J=8.7 Hz, 1H), 5.78 to 5.67 (m, 2H), 4.07 (s, 3H), 2.07 (s, 3H).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08076488B2 |
| Quelldatensatz | uspto-grants-2011_12 |
| ORD ID | ord-1125b1989b674b6ba64c42b51e42c8a1 |
| Quellennotiz | uspto-grants-2011_12 |