HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzyl Bromide → Ethyl 4-(phenylmethoxy)benzoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzyl Bromide | HCID 7498 | — |
| Reactant | Ethylparaben | HCID 8434 | — |
| Reactant | 2-Phenylacetophenone | HCID 9948 | — |
| Reactant | Cesium carbonate | HCID 10796 | — |
| Solvent | Water | HCID 962 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | Ethyl 4-(phenylmethoxy)benzoate | HCID 191414 | 100% |
Reaction Steps
35 mmol of benzyl bromide (BzBn, 35 mmol of ethyl 4-hydroxybenzoate (10), 14 g of Cs2CO3 and 40 ml of DMF were combined and stirred at RT ove night. Then the reaction mixture was poured into water and the product was collected by extraction. The organic solution was washed with brine and dried over MgSO4. After evaporation of solvent, pure product was obtained in yield of 100%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07083832B2 |
| Source dataset | uspto-grants-2006_08 |
| ORD ID | ord-424348839da04f94a84ae091f5ab15fa |
| Source note | uspto-grants-2006_08 |