2-Propenoic acid, 3-phenyl- → HCID 66974824, compound

HRID 658585Notes

Reaction equation

HRID 658585 reaction equation
[C:1]([OH:11])(=O)[CH:2]=[CH:3][C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=1.Cl.[CH3:13][C:14]1[C:18]([CH2:19][N:20]2[CH:24]=[C:23]([NH2:25])[CH:22]=[N:21]2)=[C:17]([CH3:26])[O:16][N:15]=1>>[CH3:13][C:14]1[C:18]([CH2:19][N:20]2[CH:24]=[C:23]([NH:25][C:1](=[O:11])[CH:2]=[CH:3][C:4]3[CH:5]=[CH:6][CH:7]=[CH:8][CH:9]=3)[CH:22]=[N:21]2)=[C:17]([CH3:26])[O:16][N:15]=1

Participants

3

Reactant 2

HCID 87842-Propenoic acid, 3-phenyl-HCID 574222641-((3,5-dimethylisoxazol-4-yl)methyl)-1H-pyrazol-4-amine hydrochloride

Product 1

HCID 66974824HCID 66974824, compoundYield 4%

Procedure

Prepared as in Example 4-8 from cinnamic acid and 1-((3,5-dimethylisoxazol-4-yl)methyl)-1H-pyrazol-4-amine hydrochloride (Example 4-1a). Yield 4%. MS M+H calculated 322.6, found 322.4.

Sources & evidence

ORD record
ord-04b05c97de4748959caad9b5d75ad828
Source dataset
uspto-grants-2011_12
Patent number
US08076491B2

Reaction notes

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