HRID65905

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：Nc1ccc2c(S(=O)(=O)O)cc(S(=O)(=O)O)cc2c1

HCID8356

1,3-Naphthalenedisulfonic acid, 6-amino-

C10H9NO6S2

结构：O=C(Cl)c1cc(C(=O)Cl)cc([N+](=O)[O-])c1

HCID83451

5-Nitroisophthaloyl chloride

C8H3Cl2NO4

HCID517045

Sodium Acetate

C2H3NaO2

PRODUCTS

生成物

结构：O=C(Nc1ccc2c(S(=O)(=O)[O-])cc(S(=O)(=O)[O-])cc2c1)c1cc(C(=O)Nc2ccc3c(S(=O)(=O)[O-])cc(S(=O)(=O)[O-])cc3c2)cc([N+](=O)[O-])c1.[Na+].[Na+].[Na+].[Na+]

HCID131711364

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID962

Water

H2O

PROCEDURE

实验过程

An 18.18 g portion of 6-amino-1,3-naphthalenedisulfonic acid is suspended in 200 ml of water and the pH is adjusted to 7.0 giving a solution. A 5.6 g portion of sodium acetate is dissolved in this solution and 8.18 g of 5-nitro-1,3-benzenedicarbonyl dichloride is added. The mixture is stirred for one hour, filtered and the filtrate is treated with activated carbon. The filtrate is reduced to a low volume on a rotary evaporator producing crystals. The crystals are recrystallized from water giving 6,6'-[5-nitro-1,3-phenylenebis(carbonylimino)]bis[1,3-naphthalenedisulfonic acid] tetrasodium salt.

WORKUP

后处理

additionis added
filtrationfiltered
additionthe filtrate is treated with activated carbon
customThe filtrate is reduced to a low volume on a rotary evaporator
customproducing crystals
customThe crystals are recrystallized from water

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-cf631a3b80ae4c49b0a14aa93c206573
来源数据集: uspto-grants-1978_12
DOI: 10.6084/m9.figshare.5104873.v1
专利: US04129591
来源说明: uspto-grants-1978_12

反应 SMILES

[NH2:1][C:2]1[CH:3]=[C:4]2[C:9](=[CH:10][CH:11]=1)[C:8]([S:12]([OH:15])(=[O:14])=[O:13])=[CH:7][C:6]([S:16]([OH:19])(=[O:18])=[O:17])=[CH:5]2.[C:20]([O-])(=O)[CH3:21].[Na+:24].[N+:25]([C:28]1[CH:29]=[C:30]([C:37](Cl)=[O:38])[CH:31]=[C:32]([C:34](Cl)=[O:35])[CH:33]=1)([O-:27])=[O:26]>O>[Na+:24].[Na+:24].[Na+:24].[Na+:24].[N+:25]([C:28]1[CH:29]=[C:30]([C:37]([NH:1][C:2]2[CH:3]=[C:4]3[C:9](=[CH:20][CH:21]=2)[C:8]([S:12]([O-:15])(=[O:14])=[O:13])=[CH:7][C:6]([S:16]([O-:19])(=[O:18])=[O:17])=[CH:5]3)=[O:38])[CH:31]=[C:32]([C:34]([NH:1][C:2]2[CH:3]=[C:4]3[C:9](=[CH:10][CH:11]=2)[C:8]([S:12]([O-:15])(=[O:14])=[O:13])=[CH:7][C:6]([S:16]([O-:19])(=[O:18])=[O:17])=[CH:5]3)=[O:35])[CH:33]=1)([O-:27])=[O:26]