HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydroxyamine hydrochloride → HCID 12380594, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydroxyamine hydrochloride | HCID 443297 | — |
| Reactant | Sodium Acetate | HCID 517045 | — |
| Reactant | 1-Methyl-3-cyclohexyl-6-chlorouracil | HCID 12380590 | — |
| Solvent | 2-Methoxyethanol | HCID 8019 | — |
| Product | HCID 12380594 | HCID 12380594 | 58% |
Reaction Steps
A mixture of 7 g of 1-methyl-3-cyclohexyl-6-chlorouracil, 18 g of sodium acetate (trihydrate), 7 g of hydroxylamine hydrochloride and 100 ml of methyl-cellosolve is boiled for 1 hour and, when cold, the insolubles are removed by filtration. The filtrate is concentrated and recrystallized from water-ethanol. By the above procedure is obtained 4 g of 1-methyl-3-cyclohexyl-6-hydroxyaminouracil, melting point: 153°-155° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04129654 |
| Source dataset | uspto-grants-1978_12 |
| ORD ID | ord-0845031587a44710ac33116cdc42dba8 |
| Source note | uspto-grants-1978_12 |