Acetic Anhydride → Isoxazolo(3,4-d)pyrimidine-4,6(5H,7H)-dione, 3,5,7-trimethyl-

Participants

Reaction Steps

One gram of 1,3-dimethyl-6-hydroxyaminouracil is boiled with 10 ml of acetic anhydride at 140° C. for 1 hour and, when hot, the insolubles are filtered off. The filtrate is concentrated to dryness to recover 0.7 g of the captioned compound as colorless needles. As recrystallized from ethanol, the compound melts at 200°-202° C.

Provenance & Evidence