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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 659194Generated: October 26, 2026

1,4-Dibromobutane → cis-(2-Pyrrolidin-1-yl-cyclopentyl)-carbamic acid tert-butyl ester

https://huagongshe.com/reaction/659194

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,4-DibromobutaneHCID 8056—
Reactanttert-Butyl (2-aminocyclopentyl)carbamateHCID 22667934—
Productcis-(2-Pyrrolidin-1-yl-cyclopentyl)-carbamic acid tert-butyl esterHCID 66681979—

Reaction Steps

The title compound, brown oil, MS: m/e=255.3 [(M+H)+], was prepared in accordance with the general method of intermediate E from [(1RS,2SR)-2-aminocyclopentyl-carbamic acid 1,1-dimethylethyl ester (CAS 365996-19-6) and 1,4-dibromobutane.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08080541B2
Source datasetuspto-grants-2011_12
ORD IDord-2c3105996ab4451980f828fbe77c59ba
Source noteuspto-grants-2011_12