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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 659264Generated: October 29, 2026

Tetrahydro-4H-pyran-4-one → HCID 66681522, compound

https://huagongshe.com/reaction/659264

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydro-4H-pyran-4-oneHCID 121599—
ReactantN-((1RS,2SR)-2-Amino-cyclopentyl)-2-methoxy-6-methylsulfanyl-4-trifluoromethyl-benzamideHCID 66681196—
ProductHCID 66681522HCID 66681522—

Reaction Steps

The title compound, white solid, MS: m/e=433.2 [(M+H)+], was prepared in accordance with the general method of example 11 from N-((1RS,2SR)-2-amino-cyclopentyl)-2-methoxy-6-methylsulfanyl-4-trifluoromethyl-benzamide (intermediate O) and tetrahydro-4H-pyran-4-one.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08080541B2
Source datasetuspto-grants-2011_12
ORD IDord-b27f0c6c23b44f0a8e3c843ba4a3c303
Source noteuspto-grants-2011_12