HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Methoxy-6-(trifluoromethyl)benzoic acid → cis-2-Methoxy-N-(2-pyrrolidin-1-yl-cyclopentyl)-6-trifluoromethyl-benzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Methoxy-6-(trifluoromethyl)benzoic acid | HCID 15017533 | — |
| Reactant | cis-2-Pyrrolidin-1-yl-cyclopentylamine | HCID 30820884 | — |
| Product | cis-2-Methoxy-N-(2-pyrrolidin-1-yl-cyclopentyl)-6-trifluoromethyl-benzamide | HCID 66680571 | — |
Reaction Steps
The title compound, off-white solid, MS: m/e=357.2 [(M+H)+], was prepared in accordance with the general method of example 5 from cis-2-pyrrolidin-1-yl-cyclopentylamine (intermediate Q) and 2-methoxy-6-trifluoromethylbenzoic acid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08080541B2 |
| Source dataset | uspto-grants-2011_12 |
| ORD ID | ord-680d009f7c2c4c76b436e60c80e2abf4 |
| Source note | uspto-grants-2011_12 |