HuagongsheHuagongshe Chemistry Print Report · For research reference only
cis-2-Pyrrolidin-1-yl-cyclopentylamine → 2-Cyclopropyl-N-((cis)-2-pyrrolidin-1-yl-cyclopentyl)-4,6-bis-trifluoromethyl-benzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | cis-2-Pyrrolidin-1-yl-cyclopentylamine | HCID 30820884 | — |
| Reactant | 2-Cyclopropyl-4,6-bis-trifluoromethyl-benzoic acid | HCID 58167765 | — |
| Product | 2-Cyclopropyl-N-((cis)-2-pyrrolidin-1-yl-cyclopentyl)-4,6-bis-trifluoromethyl-benzamide | HCID 51001233 | — |
Reaction Steps
The title compound, off-white solid, MS: m/e=435.3 [(M+H)+], was prepared in accordance with the general method of example 5 from cis-2-pyrrolidin-1-yl-cyclopentylamine (intermediate Q) and 2-cyclopropyl-4,6-bis-trifluoromethyl-benzoic acid (intermediate AN).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08080541B2 |
| Source dataset | uspto-grants-2011_12 |
| ORD ID | ord-4d228e2b632641d4b5be18c79d6ceed8 |
| Source note | uspto-grants-2011_12 |