Nitric Acid → 5-Chloro-2-methyl-6-nitro-1-indanone

HRID 65938Notes

Reaction equation

HRID 65938 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[C:7](=[O:11])[CH:6]([CH3:12])[CH2:5]2.[N+:13]([O-])([OH:15])=[O:14]>>[Cl:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][C:10]=1[N+:13]([O-:15])=[O:14])[C:7](=[O:11])[CH:6]([CH3:12])[CH2:5]2

Participants

3

Reactant 2

HCID 944Nitric AcidHCID 219956145-Chloro-2-methyl-2,3-dihydro-1H-inden-1-one

Product 1

HCID 227563825-Chloro-2-methyl-6-nitro-1-indanone

Procedure

According to Example 1 (a), 28.0 g (0.155 mole) of 5-chloro-2-methyl-1-indanone and 180 ml of fuming nitric acid yield the nitro compound having a melting point of from 75° to 78° C., which after recrystallization from ethanol rises to 87° to 89° C.

Sources & evidence

ORD record
ord-0faa3bdf0f024bf79037ff85cbe5db54
Source dataset
uspto-grants-1978_12
Patent number
US04129656

Reaction notes

Loading…