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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 65950Generated: October 28, 2026

Hydrochloric Acid → HCID 178485117, compound

https://huagongshe.com/reaction/65950

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantCimetidineHCID 178485005—
ProductHCID 178485117HCID 178485117—

Reaction Steps

A solution of N-cyano-N'-methyl-N"-[2-((4-methyl-5-imidazolyl)-methylthio)ethyl]guanidine (2.0 g.) in hydrochloric acid (25 ml.) was heated on the steam bath for 2 hours. Concentration followed by recrystallisation of the product from ethanol-ether afforded N-methyl-N"-[2-((4-methyl-5-imidazolyl)methylthio)ethyl]guanidine dihydrochloride (1.44 g.) m.p. 204°-206°.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04129657
Source datasetuspto-grants-1978_12
ORD IDord-f57a61dc65bf499fb2a6e1048999863f
Source noteuspto-grants-1978_12