3-Methoxybenzylamine → HCID 67092204, compound

HRID 659581Notes

Reaction equation

HRID 659581 reaction equation
[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([C:28]([F:31])([F:30])[F:29])=[C:6]([CH:27]=1)[CH2:7][N:8]1[CH2:13][CH2:12][NH:11][C:10]2[N:14]=[CH:15][C:16]([C:18]3[CH:26]=[CH:25][C:21]([C:22](O)=[O:23])=[CH:20][CH:19]=3)=[CH:17][C:9]1=2.[CH3:32][O:33][C:34]1[CH:35]=[C:36]([CH:39]=[CH:40][CH:41]=1)[CH2:37][NH2:38]>>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([C:28]([F:31])([F:29])[F:30])=[C:6]([CH:27]=1)[CH2:7][N:8]1[CH2:13][CH2:12][NH:11][C:10]2[N:14]=[CH:15][C:16]([C:18]3[CH:26]=[CH:25][C:21]([C:22]([NH:38][CH2:37][C:36]4[CH:39]=[CH:40][CH:41]=[C:34]([O:33][CH3:32])[CH:35]=4)=[O:23])=[CH:20][CH:19]=3)=[CH:17][C:9]1=2

Participants

3

Reactant 2

HCID 211563-MethoxybenzylamineHCID 469067184-{1-[5-Chloro-2-(trifluoromethyl)benzyl]-1,2,3,4-tetrahydropyrido[2,3-b]pyrazin-7-yl}benzoic acid

Product 1

HCID 67092204HCID 67092204, compound

Procedure

4-{1-[5-chloro-2-(trifluoromethyl)benzyl]-1,2,3,4-tetrahydropyrido[2,3-b]pyrazin-7-yl}benzoic acid was reacted with 3-methoxybenzylamine as in General Procedure 10 to give the title compound. LCMS: m/z=566.97 (M+H+); retention time=0.91 minutes.

Sources & evidence

ORD record
ord-c15de340725643c0bdfa28558927bfd6
Source dataset
uspto-grants-2011_12
Patent number
US08080561B2

Reaction notes

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