反应详情

A 100-mL round-bottom flask was placed a solution of 6-nitrobiphenyl-2-carbaldehyde (6.2 g, 27.31 mmol, 1.00 equiv) in 1,2-dichlorobenzene (60 mL). To the mixture was added PPh3 (17.9 g, 68.32 mmol, 2.50 equiv) and the mixture was heated to reflux for 30 hours. Upon completion, the resulting mixture was concentrated on a rotary evaporator to give a residue that was purified by silica gel column chromatography affording 9H-carbazole-4-carbaldehyde as yellow solid (3 g, 56%).

1. customA 100-mL round-bottom flask was placed
2. temperaturethe mixture was heated
3. temperatureto reflux for 30 hours
4. concentrationUpon completion, the resulting mixture was concentrated on a rotary evaporator
5. customto give a residue that
6. customwas purified by silica gel column chromatography