HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-(2-Methyl-5-nitrophenyl)acetamide → 4-[2-(2-Methyl-5-nitro-phenylamino)-oxazol-5-yl]-benzonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-(2-Methyl-5-nitrophenyl)acetamide | HCID 76144 | — |
| Reactant | 2-Acetylamino-4-aminotoluene | HCID 79492 | — |
| Reactant | 4-[2-(5-Amino-2-methyl-phenylamino)-oxazol-5-yl]-benzonitrile | HCID 17757346 | — |
| Product | 4-[2-(2-Methyl-5-nitro-phenylamino)-oxazol-5-yl]-benzonitrile | HCID 24871994 | 83% |
Reaction Steps
The same procedure outlined above in the preparation of 4-[2-(5-Amino-2-methyl-phenylamino)-oxazol-5-yl]-benzonitrile was used. However N-(2-methyl-5-nitro-phenyl)-acetamide was used instead N-(5-Amino-2-methyl-phenyl)-acetamide. Yield=83%. m.p.>228° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08080669B2 |
| Source dataset | uspto-grants-2011_12 |
| ORD ID | ord-0d109a57438c4e769d56ccca9a07b43d |
| Source note | uspto-grants-2011_12 |