反应详情

152 g. of 1-methyl-5-phenylpyrazolo[1,5-a]pyrimidin-7(1H)-one (0.67 mol.) in 500 ml. of diphenyl ether are heated at 250°, while stirring, for 90 minutes. After standing overnight, the crystallized 2-methyl-6-phenyl-2H-pyrazolo[3,4-b]pyridin-4-ol is filtered off, washed with ether and dried at 70°, yield; 146.6 g. (96%); m.p.241°-243°. A sample recrystallized from acetonitrile melts at 242°-244°.

1. waitAfter standing overnight
2. filtrationthe crystallized 2-methyl-6-phenyl-2H-pyrazolo[3,4-b]pyridin-4-ol is filtered off
3. washwashed with ether
4. customdried at 70°
5. customA sample recrystallized from acetonitrile melts at 242°-244°