Diphenyl Ether → HCID 178515555, compound

HRID 65995Notes

Reaction equation

HRID 65995 reaction equation
[C:1]1([N:7]2[N:11]3[C:12](=[O:22])[CH:13]=[C:14]([C:16]4[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=4)[N:15]=[C:10]3[CH:9]=[CH:8]2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.C1(OC2C=CC=CC=2)C=CC=CC=1>>[C:1]1([N:7]2[CH:8]=[C:9]3[C:10]([N:15]=[C:14]([C:16]4[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=4)[CH:13]=[C:12]3[OH:22])=[N:11]2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

Participants

3

Reactant 2

HCID 7583Diphenyl EtherHCID 133591001,5-Diphenylpyrazolo[1,5-a]pyrimidin-7(1H)-one

Product 1

HCID 178515555HCID 178515555, compound

Procedure

6.5 g. of 1,5-diphenylpyrazolo[1,5-a]pyrimidin7(1H)-one (0.0226 mol.) and 18 g. of diphenyl ether are heated at 250°-260° for 90 minutes. After standing overnight, the crystallized 2,6-diphenyl-2H-pyrazolo[3,4-b]pyridin-4-ol is filtered off, washed with ethanol and dried at 80°, yield: 6.1 g. (94%); m.p. 280°-281°.

Workup

  1. filtrationthe crystallized 2,6-diphenyl-2H-pyrazolo[3,4-b]pyridin-4-ol is filtered off
  2. washwashed with ethanol
  3. customdried at 80°

Sources & evidence

ORD record
ord-55ee440295be45aaac4d501a4bc28f2f
Source dataset
uspto-grants-1978_12
Patent number
US04129738

Reaction notes

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