HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cyclohexylphenylglycolic acid, (-)- → (R)-Cyclohexyl-hydroxy-phenyl-acetic acid (R)-(1-aza-bicyclo[2.2.2]oct-3-yl)ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cyclohexylphenylglycolic acid, (-)- | HCID 777377 | — |
| Reactant | (S)-cyclohexyl-hydroxy-thiophen-2-yl-acetic acid (R)-(1-aza-bicyclo[2.2.2]oct-3-yl)ester | HCID 66959049 | — |
| Product | (R)-Cyclohexyl-hydroxy-phenyl-acetic acid (R)-(1-aza-bicyclo[2.2.2]oct-3-yl)ester | HCID 10831243 | — |
Reaction Steps
This compound is prepared analogously to (S)-cyclohexyl-hydroxy-thiophen-2-yl-acetic acid (R)-(1-aza-bicyclo[2.2.2]oct-3-yl)ester by replacing (S)-cyclohexyl-hydroxy-thiophen-2-yl-acetic acid with (R)-cyclohexyl-hydroxy-phenyl-acetic acid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08084463B2 |
| Source dataset | uspto-grants-2011_12 |
| ORD ID | ord-9ee0df1259764a9aad2bc237d46a2a40 |
| Source note | uspto-grants-2011_12 |