Butyl disulfide → HCID 178454949, compound

HRID 660149Notes

Reaction equation

HRID 660149 reaction equation
[CH3:1][S:2][C:3]1[C:4]([C:8]2[CH:9]=[N:10][CH:11]=[CH:12][CH:13]=2)=[N:5][NH:6][CH:7]=1.[CH2:14](SSCCCC)[CH2:15][CH2:16]C.IC1C(C2C=NC=CC=2)=NNC=1>C(OCC)(=O)C.C(OCC)C>[CH2:1]([S:2][C:3]1[C:4]([C:8]2[CH:9]=[N:10][CH:11]=[CH:12][CH:13]=2)=[N:5][NH:6][CH:7]=1)[CH2:14][CH2:15][CH3:16]

Participants

5

Reactant 3

HCID 12386Butyl disulfideHCID 178503312HCID 178503312, compoundHCID 178506560HCID 178506560, compound2×

Product 1

HCID 178454949HCID 178454949, compoundYield 18.4%

Reagents, catalysts & solvents 1

HCID 21584169Diethylether ethylacetateSolvent

Procedure

Compound 21F was prepared following the procedure as described for the synthesis of compound 21A (see Scheme 3) using 1-butyldisulfanyl-butane as the disulfide and 3-(4-iodo-1H-pyrazol-3-yl)-pyridine (compound 20B). (flash chromatography conditions ethyl acetate/diethyl ether 3/1).

Sources & evidence

ORD record
ord-5cd1dff7ccf94545a2b9e46a5563380d
Source dataset
uspto-grants-2011_12
Patent number
US08084473B2

Reaction notes

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