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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 660247Generated: October 29, 2026

3-Fluoro-6-(methylamino)pyridine → Methyl 5-chloro-2-{[(5-fluoropyridin-2-yl)(methyl)amino]methyl}benzoate

https://huagongshe.com/reaction/660247

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Fluoro-6-(methylamino)pyridineHCID 59149667—
ReactantMethyl 2-(bromoethyl)-5-chlorobenzoateHCID 68983888—
ProductMethyl 5-chloro-2-{[(5-fluoropyridin-2-yl)(methyl)amino]methyl}benzoateHCID 68863698—

Reaction Steps

The title compound was prepared according to the procedure described in step 1 of Example 22 from methyl 2-(bromoethyl)-5-chlorobenzoate and 5-fluoro-N-methylpyridin-2-amine (step 1):

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08084476B2
Source datasetuspto-grants-2011_12
ORD IDord-600c13ef77a24d91a559d2448773861c
Source noteuspto-grants-2011_12