反应详情

Methyl-2-(4-hydroxy-3-nitrophenyl)acetate (2.31 g, 10.9 mmol) was dissolved in THF (20 mL) and MeOH (20 mL) and 10% palladium on carbon (210 mg) was added slowly at RT. The reaction mixture was hydrogenated for 2 h at 39 psi hydrogen pressure, filtered through Celite and washed with MeOH. The solvent was removed under a vacuum and the residue purified by means of column chromatography (n-hexane/EA=2:1).

1. filtrationfiltered through Celite
2. washwashed with MeOH
3. customThe solvent was removed under a vacuum
4. customthe residue purified by means of column chromatography (n-hexane/EA=2:1)