反应详情

Ethyl 2-(4-hydroxy-3-nitrophenyl)propanoate (260 mg, 1.09 mmol) in THF (6 mL) and ethanol (6 mL) was slowly added 10% Pd/C (29 mg) at room temperature. The mixture was hydrogenated for 2 hours at 43 psi and then filtered with celite pad and washed with EtOAc. The filtrate was concentrated in vacuo. The residue was purified by column chromatography eluting with n-Hexane/EtOAc=1/1.

1. customat room temperature
2. filtrationfiltered with celite pad
3. washwashed with EtOAc
4. concentrationThe filtrate was concentrated in vacuo
5. customThe residue was purified by column chromatography
6. washeluting with n-Hexane/EtOAc=1/1