反应详情

Chroman-2-carboxylic acid (4.3 g, 24 mmol) in THF (70 mL) was combined with 1M LAH in THF (30 mL, 30 mmol) and stirred at room temperature for 2 h. The reaction mixture was quenched with water and then stirred for 2 hours. The THF solution was decanted from the solid, which was washed with fresh THF. The combined THF solution was dried (Na2SO4) and evaporated in vacuo to yield chroman-2-yl-methanol as an oil.

1. customThe reaction mixture was quenched with water
2. stirringstirred for 2 hours
3. customThe THF solution was decanted from the solid, which
4. washwas washed with fresh THF
5. dry with materialThe combined THF solution was dried (Na2SO4)
6. customevaporated in vacuo