HRID660529

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID20716152

tert-Butyl 3-(iodomethyl)piperidine-1-carboxylate

C11H20INO2

结构：C[Si](C)(C)CCN1C(=O)CN(c2ccc(I)cc2OCc2ccccc2)S1(=O)=O

HCID66756937

未命名化合物

PRODUCTS

生成物

结构：CC(C)(C)OC(=O)N1CCCC(Cc2ccc(N3CC(=O)N(CC[Si](C)(C)C)S3(=O)=O)c(OCc3ccccc3)c2)C1

HCID68842307

未命名化合物

PROCEDURE

实验过程

The title compound is prepared from 3-iodomethylpiperidine-1-carboxylic acid tert-butyl ester and 5-(2-benzyloxy-4-iodophenyl)-1,1-dioxo-2-(2-trimethylsilanylethyl)-1,2,5-thiadiazolidin-3-one analogous to the method used in Example 57, step B.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-1fc5368b6f3848b5b4586cad36e17778
来源数据集: uspto-grants-2011_12
DOI: 10.6084/m9.figshare.5104873.v1
专利: US08084448B2
来源说明: uspto-grants-2011_12

反应 SMILES

[C:1]([O:5][C:6]([N:8]1[CH2:13][CH2:12][CH2:11][CH:10]([CH2:14]I)[CH2:9]1)=[O:7])([CH3:4])([CH3:3])[CH3:2].[CH2:16]([O:23][C:24]1[CH:29]=[C:28](I)[CH:27]=[CH:26][C:25]=1[N:31]1[S:35](=[O:37])(=[O:36])[N:34]([CH2:38][CH2:39][Si:40]([CH3:43])([CH3:42])[CH3:41])[C:33](=[O:44])[CH2:32]1)[C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1>>[C:1]([O:5][C:6]([N:8]1[CH2:13][CH2:12][CH2:11][CH:10]([CH2:14][C:28]2[CH:27]=[CH:26][C:25]([N:31]3[CH2:32][C:33](=[O:44])[N:34]([CH2:38][CH2:39][Si:40]([CH3:43])([CH3:42])[CH3:41])[S:35]3(=[O:37])=[O:36])=[C:24]([O:23][CH2:16][C:17]3[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=3)[CH:29]=2)[CH2:9]1)=[O:7])([CH3:4])([CH3:3])[CH3:2]