HuagongsheHuagongshe Chemistry Print Report · For research reference only
Tert-butyl 3-(iodomethyl)piperidine-1-carboxylate → 3-{3-Benzyloxy-4-[1,1,4-trioxo-5-(2-trimethylsilanylethyl)-1,2,5-thiadiazolidin-2-yl]-benzyl}-piperidine-1-carboxylic Acid Tert-butyl Ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Tert-butyl 3-(iodomethyl)piperidine-1-carboxylate | HCID 20716152 | — |
| Reactant | 5-(2-Benzyloxy-4-iodophenyl)-1,1-dioxo-2-(2-trimethylsilanylethyl)-1,2,5-thiadiazolidin-3-one | HCID 66756937 | — |
| Product | 3-{3-Benzyloxy-4-[1,1,4-trioxo-5-(2-trimethylsilanylethyl)-1,2,5-thiadiazolidin-2-yl]-benzyl}-piperidine-1-carboxylic Acid Tert-butyl Ester | HCID 68842307 | — |
Reaction Steps
The title compound is prepared from 3-iodomethylpiperidine-1-carboxylic acid tert-butyl ester and 5-(2-benzyloxy-4-iodophenyl)-1,1-dioxo-2-(2-trimethylsilanylethyl)-1,2,5-thiadiazolidin-3-one analogous to the method used in Example 57, step B.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08084448B2 |
| Source dataset | uspto-grants-2011_12 |
| ORD ID | ord-1fc5368b6f3848b5b4586cad36e17778 |
| Source note | uspto-grants-2011_12 |