HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 24969059, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | HCID 24969058 | HCID 24969058 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | HCID 24969059 | HCID 24969059 | — |
Reaction Steps
To a suspension of 3-[3-hydroxy-4-(1,1,4-trioxo-1,2,5-thiadiazolidin-2-yl)-benzyl]-piperidine-1-carboxylic acid tert-butyl ester (24 mg, 0.052 mmol) in ether (1.5 mL) is added 2 mL of HCl in dioxane (4 M) and the mixture is stirred at RT for 18 h. The solvent is removed under reduced pressure to give the hydrochloride salt of the title compound: (M−1)−=324.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08084448B2 |
| Source dataset | uspto-grants-2011_12 |
| ORD ID | ord-73c626ac225d4422ba1ac779d040c483 |
| Source note | uspto-grants-2011_12 |