HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → 2-(3-Benzyloxy-4-nitrobenzyl)-cyclohexanone Oxime
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Hydroxyamine hydrochloride | HCID 443297 | — |
| Reactant | Sodium Acetate | HCID 517045 | — |
| Reactant | 2-(3-Benzyloxy-4-nitrobenzyl)-cyclohexanone | HCID 68839316 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 2-(3-Benzyloxy-4-nitrobenzyl)-cyclohexanone Oxime | HCID 86632574 | — |
Reaction Steps
A mixture of 2-(3-benzyloxy-4-nitrobenzyl)-cyclohexanone (1.0 g, 2.95 mmol), hydroxylamine hydrochloride (407 mg, 5.9 mmol) and sodium acetate (726 mg, 8.85 mmol) in MeOH (20 mL)/water (4 mL) is stirred at RT for 18 h. The resulting precipitate is filtered and washed with water to give the title compound as a yellow solid: (M+1)+=355.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08084448B2 |
| Source dataset | uspto-grants-2011_12 |
| ORD ID | ord-77552b5751b541f8a90ecf2119f0275c |
| Source note | uspto-grants-2011_12 |