反应详情

A mixture of 2-(3-benzyloxy-4-nitrobenzyl)-cyclohexanone (1.0 g, 2.95 mmol), hydroxylamine hydrochloride (407 mg, 5.9 mmol) and sodium acetate (726 mg, 8.85 mmol) in MeOH (20 mL)/water (4 mL) is stirred at RT for 18 h. The resulting precipitate is filtered and washed with water to give the title compound as a yellow solid: (M+1)+=355.

1. filtrationThe resulting precipitate is filtered
2. washwashed with water