HCID 68842585, compound → HCID 57777404, compound

Participants

Reaction Steps

A solution of 2{(E)-3-[3-benzyloxy-4-(1,1,4-trioxo-1,2,5-thiadiazolidin-2-yl)-phenyl]-acryloylamino}-2-methylpropionic acid (40 mg) in EtOAc (4 mL) is hydrogenated at 1 atm over 20 mg of 10% Pd/C for 24 h. The catalyst is filtered through Celite and the solvent removed under reduced pressure to give the title compound as a yellow solid: (M−1)−=384, HPLC retention time=0.71 min. (Method A).

Provenance & Evidence