HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(4-Aminobutoxy)-6-benzyloxybenzoic Acid Methyl Ester → 2-(4-{(S)-2-Acetylamino-3-[3-benzyloxy-4-(1,1,4-trioxo-1,2,5-thiadiazolidin-2-yl)-phenyl]-propionylamino}-butoxy)-6-benzyloxybenzoic Acid Methyl Ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(4-Aminobutoxy)-6-benzyloxybenzoic Acid Methyl Ester | HCID 68429372 | — |
| Reactant | (S)-2-Acetylamino-3-[3-benzyloxy-4-(1,1,4-trioxo-1,2,5-thiadiazolidin-2-yl)-phenyl]-propionic Acid | HCID 68838960 | — |
| Product | 2-(4-{(S)-2-Acetylamino-3-[3-benzyloxy-4-(1,1,4-trioxo-1,2,5-thiadiazolidin-2-yl)-phenyl]-propionylamino}-butoxy)-6-benzyloxybenzoic Acid Methyl Ester | HCID 68922127 | — |
Reaction Steps
The title compound is prepared using (S)-2-acetylamino-3-[3-benzyloxy-4-(1,1,4-trioxo-1,2,5-thiadiazolidin-2-yl)-phenyl]-propionic acid and 2-(4-aminobutoxy)-6-benzyloxybenzoic acid methyl ester (Example 110, step C) analogous to Example 131, step C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08084448B2 |
| Source dataset | uspto-grants-2011_12 |
| ORD ID | ord-1e2156cde31e4beabed31d8f1ec4bbb6 |
| Source note | uspto-grants-2011_12 |