5-(2-Benzyloxy-4-iodophenyl)-1,1-dioxo-2-(2-trimethylsilanylethyl)-1,2,5-thiadiazolidin-3-one → HCID 57777373, compound

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Reaction Steps

The title compound is prepared from 5-(2-benzyloxy-4-iodophenyl)-1,1-dioxo-2-(2-trimethylsilanylethyl)-1,2,5-thiadiazolidin-3-one and (4-iodobutane-1-sulfonyl)-benzene analogous to Example 57, steps B, C and D: (M−1)−=423. 1H NMR (400 MHz, DMSO-D6) δ ppm 1.49-1.60 (m, 4 H) 2.40 (t, J=6.69 Hz, 2 H) 4.01 (s, 2 H) 6.46 (s, 1 H) 6.58 (s, 1 H) 7.21 (d, J=7.83 Hz, 1 H) 7.65 (t, J=7.58 Hz, 2 H) 7.71-7.77 (m, 1 H) 7.85-7.90 (m, 2 H)

Provenance & Evidence