HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(3-Benzyloxy-4-nitrophenyl)-2-methylpentan-3-one → 1-(4-Amino-3-benzyloxyphenyl)-2-methylpentan-3-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(3-Benzyloxy-4-nitrophenyl)-2-methylpentan-3-one | HCID 68839993 | — |
| Catalyst | Platinum | HCID 23939 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | 1-(4-Amino-3-benzyloxyphenyl)-2-methylpentan-3-one | HCID 68837957 | — |
Reaction Steps
A mixture of 1-(3-benzyloxy-4-nitrophenyl)-2-methylpentan-3-one (450 mg) and Pt/C (22 mg) in EtOAc (15 mL) is hydrogenated at 1 atm for 18 h. The catalyst is filtered and the filtrate evaporated to give the title compound which is used directly in the next step.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08084448B2 |
| Source dataset | uspto-grants-2011_12 |
| ORD ID | ord-3252999f746542b580a75cab8b4636cb |
| Source note | uspto-grants-2011_12 |