HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium tert-butoxide → HCID 68838475, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium tert-butoxide | HCID 23665647 | — |
| Reactant | Methyl N-(aminosulfonyl)-N-(2-(benzyloxy)-4-{2-oxo-2-[2-(trimethylsilyl)ethoxy]ethoxy}phenyl)glycinate | HCID 68840538 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 68838475 | HCID 68838475 | — |
Reaction Steps
To a solution of methyl N-(aminosulfonyl)-N-(2-(benzyloxy)-4-{2-oxo-2-[2-(trimethylsilyl)ethoxy]ethoxy}phenyl)glycinate in THF is added potassium t-butoxide (1.1 equivalent) in THF dropwise. The mixture is stirred at RT for 18 h. The solvent is removed under reduced pressure to afford the title compound which is used directly in the next step.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08084448B2 |
| Source dataset | uspto-grants-2011_12 |
| ORD ID | ord-0e59aa6acd894632ac7d2a82f4f6c89a |
| Source note | uspto-grants-2011_12 |