Hydrochloric Acid → HCID 58012134, compound

Participants

Reaction Steps

205 mg (0.67 mmol) of ethyl 4-ethyl-[3-(4-methoxyphenyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-acetate from Example 109A are dissolved in 0.46 ml of methanol, treated with 0.18 ml 20% aqueous potassium hydroxide and stirred overnight. Next it is brought to a pH of 1 with 1 N hydrochloric acid, evaporated and the residue dried in vacuo. 207 mg of the target compound is thus obtained as crude product, which is further reacted as such.

Provenance & Evidence