反应详情

温度

50 °C

Under an argon atmosphere, 19.00 g (111.4 mmol) of 4-chlorobenzoic acid hydrazide are placed in 150 ml THF. 9.44 g (111.6 mmol) of allyl isocyanate, dissolved in 110 ml THF, are added dropwise at 50° C. and the mixture further stirred overnight at 50° C. The solvent is then evaporated in vacuo, diethyl ether is added to the residue and the solid formed is isolated and purified by filtration and further washing with diethyl ether. 26.80 g (95% of theory) of the target compound are thus obtained.

1. additionare added dropwise at 50° C.
2. customThe solvent is then evaporated in vacuo, diethyl ether
3. additionis added to the residue
4. customthe solid formed
5. customis isolated
6. filtrationpurified by filtration
7. washfurther washing with diethyl ether
8. custom26.80 g (95% of theory) of the target compound are thus obtained