HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 58012031, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | HCID 58011795 | HCID 58011795 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | HCID 58012031 | HCID 58012031 | — |
Reaction Steps
The compound from Example 365 (22 mg, 37 μmol) is stirred overnight at RT with 1 ml of a 4 M hydrogen chloride solution in dioxan. The solvent is then removed on the rotary evaporator. The residue is taken up in DMSO and purified by preparative HPLC (Method 20). 14 mg (70% of theory) of the title compound are obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08084481B2 |
| Source dataset | uspto-grants-2011_12 |
| ORD ID | ord-18979c944aec4eedaa5ab673afe99b7d |
| Source note | uspto-grants-2011_12 |