反应详情

A solution of 4.1 g of cis-1,2,3,4-tetrahydro-2-[[4-(2-methoxyphenyl)-1-piperazinyl]methyl]-1-naphthalenol in 150 ml of absolute ethanol is treated with 4.9 ml of a solution of 4.8 N hydrochloric acid in ether. The mixture is warmed on a steam bath for 15 minutes, cooled and filtered. Recrystallization from ethanol/ether yields 3.5 g of the title compound, melting point 199°-200° C.

1. temperatureThe mixture is warmed on a steam bath for 15 minutes
2. temperaturecooled
3. filtrationfiltered
4. customRecrystallization from ethanol/ether