HRID661097

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID67184

1-Bromopyrrolidine-2,5-dione

C4H4BrNO2

HCID1201417

2-Thiazolamine, 4-(trifluoromethyl)-

C4H3F3N2S

HCID15710701

5-Bromo-4-(trifluoromethyl)-1,3-thiazol-2-amine

C4H2BrF3N2S

结构：N[C@]1(NCCCc2ccc(Cl)cc2)NC(C(F)(F)F)=C(c2ccc3cnccc3c2)S1

HCID131729329

未命名化合物

PRODUCTS

生成物

结构：Cn1ncc2ccc(-c3cnc(NC[C@@H](N)Cc4ccc(C(F)(F)F)cc4)s3)cc21

HCID46880371

未命名化合物

PROCEDURE

实验过程

Example 168, N—((S)-2-amino-3-(4-chlorophenyl)propyl-5-(isoquinolin-6-yl)-4-(trifluoromethyl)thiazol-2-amine: The title compound was synthesized in a manner similar manner to that described for Example 165 using 5-bromo-4-(trifluoromethyl)thiazol-2-amine as the starting material which was synthesized by treating 4-(trifluoromethyl)thiazol-2-amine with N-bromosuccinimide. Theoretical (M+H) 463.1 found 463.1.

WORKUP

后处理

customwas synthesized