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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 661124Generated: October 27, 2026

tert-butyl N-(5-(tributylstannyl)-1,3-thiazol-2-yl)carbamate → tert-Butyl 5-(cinnolin-6-yl)thiazol-2-ylcarbamate

https://huagongshe.com/reaction/661124

Reaction equation

Participants

RoleNameHCIDCharge
Reactanttert-butyl N-(5-(tributylstannyl)-1,3-thiazol-2-yl)carbamateHCID 2763269—
Reactant6-BromocinnolineHCID 11229560—
Producttert-Butyl 5-(cinnolin-6-yl)thiazol-2-ylcarbamateHCID 8661378173.1%

Reaction Steps

The title compound (0.24 g, 60%) was synthesized in a manner similar to that described in Example 253 from 6-bromocinnoline (0.25 g, 1.0 mmol) and tert-butyl 5-(tributylstannyl)thiazol-2-ylcarbamate (0.90 g, 1.5 eq). LCMS (API-ES) m/z (%): 329.4 (100%, M++H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08084479B2
Source datasetuspto-grants-2011_12
ORD IDord-4965d1383b964c8f9eae123414ee8795
Source noteuspto-grants-2011_12