Hydrochloric Acid → HCID 131711377, compound

HRID 66113Notes

Reaction equation

HRID 66113 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[C:5]2[C:9](=[CH:10][C:11]=1[O:12][CH3:13])[CH:8](O)[CH:7]([CH2:15][N:16]1[CH2:21][CH2:20][N:19]([C:22]3[CH:27]=[CH:26][CH:25]=[CH:24][C:23]=3[O:28][CH3:29])[CH2:18][CH2:17]1)[CH2:6]2.[ClH:30]>C(O)C>[ClH:30].[CH3:13][O:12][C:11]1[CH:10]=[C:9]2[C:5](=[CH:4][C:3]=1[O:2][CH3:1])[CH:6]=[C:7]([CH2:15][N:16]1[CH2:21][CH2:20][N:19]([C:22]3[CH:27]=[CH:26][CH:25]=[CH:24][C:23]=3[O:28][CH3:29])[CH2:18][CH2:17]1)[CH2:8]2

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 227555592,3-Dihydro-5,6-dimethoxy-2-[[4-(2-methoxyphenyl)-1-piperazinyl]methyl]-1H-inden-1-ol

Product 1

HCID 131711377HCID 131711377, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

2,3-Dihydro-5,6-dimethoxy-2-[[4-(2-methoxyphenyl)-1-piperazinyl]methyl]-1H-inden-1-ol (5.2g, prepared as described in Example 8) is dissolved in ethanol, chilled and treated with an excess of ethereal hydrogen chloride.

Workup

  1. temperaturechilled

Sources & evidence

ORD record
ord-b3c6227100b048b88afe708a2079074c
Source dataset
uspto-grants-1978_12
Patent number
US04130646

Reaction notes

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