Hydrochloric Acid → 2-[o-(beta-Dimethylamino-ethoxy)-styryl]-pyrazine

HRID 66124Notes

Reaction equation

HRID 66124 reaction equation
Cl[CH2:2][CH2:3][O:4][C:5]1[CH:18]=[CH:17][CH:16]=[CH:15][C:6]=1[CH:7]=[CH:8][C:9]1[CH:14]=[N:13][CH:12]=[CH:11][N:10]=1.[CH3:19][NH:20][CH3:21].Cl>>[CH3:19][N:20]([CH3:21])[CH2:2][CH2:3][O:4][C:5]1[CH:18]=[CH:17][CH:16]=[CH:15][C:6]=1[CH:7]=[CH:8][C:9]1[CH:14]=[N:13][CH:12]=[CH:11][N:10]=1

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 674DimethylamineHCID 53730203HCID 53730203, compound

Product 1

HCID 544379222-[o-(beta-Dimethylamino-ethoxy)-styryl]-pyrazine

Procedure

2-[o-(β-Dimethylamino-ethoxy)-styryl]-pyrazine was prepared from 2-[o-(β-chloro-ethoxy)styryl]-pyrazine and dimethylamine, and the free base was converted into its monohydrochloride, yielding 54% of theory of the compound of the formula ##STR13## which had a melting point of 194°-195° C.

Workup

  1. customyielding 54% of theory of the compound of the formula ##STR13## which

Sources & evidence

ORD record
ord-6529f1be7b6642d9a612ec9367036526
Source dataset
uspto-grants-1978_12
Patent number
US04130650

Reaction notes

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