m-Chloroperbenzoic acid → {3-(3-Ethoxy-1,2,4-oxadiazol-5-yl)-5-[4-(2,2,2-trifluoroethyl)phenyl]piperidin-1-yl}(1-oxidothio-morpholin-4-yl)methanone

Participants

Reaction Steps

129 mg (0.266 mmol) of the compound from Example 64 were reacted according to General Method 2 with 82.7 mg (0.240 mmol) of meta-chloroperbenzoic acid. Enantiomer separation of 132 mg of the racemate according to Method 8D gave 51.0 mg of the title compound from Example 65 (enantiomer 1) and 53.0 mg of the title compound from Example 66 (enantiomer 2).

Provenance & Evidence