反应详情

A mixture of 4,7-dihydro-4,7-dioxo-6-ethoxy-1-ethyl-1H-cyclohepta[b]pyridine-2-carboxylic acid (5.3 g, described in Example 13) and 19% hydrochloric acid (50 ml) is refluxed for 1 hr and cooled to room temperature. The precipitate is collected and washed with water to give the title compound, mp > 280° C.

1. temperatureis refluxed for 1 hr
2. customThe precipitate is collected
3. washwashed with water