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HRID661555

反应详情

EQUATION

反应方程式

HRID 661555 的结构方程式

REACTANTS

反应物

2
结构：CCC[C@]1(C=O)CC(O[Si](C)(C)C(C)(C)C)CN1C(=O)OC(C)(C)C
HCID86620863

未命名化合物

结构：Clc1ccc([Mg]Br)cc1Cl
HCID178478192

未命名化合物

PRODUCTS

生成物

1
结构：CCC[C@]1(C(O)c2ccc(Cl)c(Cl)c2)CC(O[Si](C)(C)C(C)(C)C)CN1C(=O)OC(C)(C)C
HCID66687943

未命名化合物

PROCEDURE

实验过程

(R)-4-(tert-Butyl-dimethyl-silanyloxy)-2-propyl-2-[(3,4-dichloro-phenyl)-hydroxy-methyl]-pyrrolidine-1-carboxylic acid tert-butyl ester was prepared by reaction of 3,4-dichlorophenyl magnesium bromide with (R)-4-(tert-Butyl-dimethyl-silanyloxy)-2-formyl-2-propyl-pyrrolidine-1-carboxylic acid tert-butyl ester following the procedure of step 1 of Example 11.