4-Oxobutanoic acid → Isopropylaminium

HRID 66156Notes

Reaction equation

HRID 66156 reaction equation
[O:1]=[CH:2][CH2:3][CH2:4][C:5]([OH:7])=[O:6].[CH:8]([NH2:11])([CH3:10])[CH3:9]>C1C=CC=CC=1>[CH:8]([NH3+:11])([CH3:10])[CH3:9].[O:1]=[CH:2][CH2:3][CH2:4][C:5]([O-:7])=[O:6]

Participants

5

Reactant 2

HCID 11124-Oxobutanoic acidHCID 6363Isopropylamine

Product 2

HCID 3364502IsopropylaminiumHCID 95432384-Oxobutanoate

Reagents, catalysts & solvents 1

HCID 241BenzeneSolvent

Procedure

100 Mg. of 4-(6,11-dihydrodibenzo-[b.e.]-thiepin-11-one-3-yl)-4-oxobutyric acid in 15 ml. of hot benzene is treated with 60 mg. of isopropyl amine. The solution is allowed to cool to room temperature and the product is filtered off, washed with ether and dried to yield isopropylammonium 4-(6,11-dihydrodibenzo-[b.e.]-thiepin-11-one-3-yl)-4-oxobutyrate.

Workup

  1. filtrationthe product is filtered off
  2. washwashed with ether
  3. customdried

Sources & evidence

ORD record
ord-9fbbeabf522d4d0bb714410dabecfb77
Source dataset
uspto-grants-1978_12
Patent number
US04130654

Reaction notes

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