Fumarate → 3',4'-Dichloro-2-(2-pyrrolidinylidene)-acetophenone

HRID 66158Notes

Reaction equation

HRID 66158 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([C:9](=NC2CCCCC2)[CH:10]=[C:11]2[CH2:15][CH2:14][CH2:13][NH:12]2)[CH:5]=[CH:6][C:7]=1[Cl:8].C([O-])(=O)/C=C/C([O-])=[O:27]>C(O)(C)C.CCOCC>[Cl:1][C:2]1[CH:3]=[C:4]([C:9](=[O:27])[CH:10]=[C:11]2[CH2:15][CH2:14][CH2:13][NH:12]2)[CH:5]=[CH:6][C:7]=1[Cl:8]

Participants

4

Reactant 2

HCID 5460307FumarateHCID 1371959212-[2-(3,4-Dichlorophenyl)-2-(cyclohexylimino)-ethylidene]-pyrrolidine-

Product 1

HCID 705731673',4'-Dichloro-2-(2-pyrrolidinylidene)-acetophenone

Reagents, catalysts & solvents 1

HCID 22147583Diethyl ether 2-propanolSolvent

Procedure

With the use of 76.8 g (0.3 mole) of 3',4'-dichloro-2-(2-pyrrolidinylidene)-acetophenone, there is obtained in an analogous manner 2-[2-(3,4-dichlorophenyl)-2-(cyclohexylimino)-ethylidene]-pyrrolidine-(1:1)-fumarate, m.p. 208°-209° (from isopropanol/ether).

Sources & evidence

ORD record
ord-5c5d6aca6ead40eb8ac759af48ed87ac
Source dataset
uspto-grants-1978_12
Patent number
US04130652

Reaction notes

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