Sodium Chloride → HCID 58579818, compound

HRID 661762Notes

Reaction equation

HRID 661762 reaction equation
[C:1]1([N:7]=[C:8]([S:15][CH:16]([CH2:22][CH3:23])[CH:17]([CH3:21])[CH2:18][CH2:19][CH3:20])[C:9]#[C:10][Si](C)(C)C)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.C(=O)([O-])[O-].[K+].[K+].[Cl-].[Na+]>CO>[C:1]1([N:7]=[C:8]([S:15][CH:16]([CH2:22][CH3:23])[CH:17]([CH3:21])[CH2:18][CH2:19][CH3:20])[C:9]#[CH:10])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

Participants

5

Reactant 3

HCID 5234Sodium ChlorideHCID 11430Potassium CarbonateHCID 58579789HCID 58579789, compound

Product 1

HCID 58579818HCID 58579818, compoundYield 92.7%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

1-ethyl-2-methylpentyl N-phenyl-3-(trimethylsilyl)thiopropynimidate (0.60 g) was dissolved to methanol (12 mL), small amount of potassium carbonate was added to the solution under ice-cooling, and then stirred for 30 minutes. The reaction mixture was poured into saturated aqueous solution of sodium chloride. It was extracted with ethyl acetate. Obtained organic layer was washed with water, dried, and the solvent was distilled off to obtain 1-ethyl-2-methylpentyl N-(phenyl)thiopropynimidate (0.44 g).

Workup

  1. additionwas added to the solution under ice-
  2. temperaturecooling
  3. extractionIt was extracted with ethyl acetate
  4. washObtained organic layer was washed with water
  5. customdried
  6. distillationthe solvent was distilled off

Sources & evidence

ORD record
ord-3f7a98399b684a119a4377b42dad63ed
Source dataset
uspto-grants-2011_12
Patent number
US08084644B2

Reaction notes

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