反应详情

A mixture of 1.05 g. (3 mmol) of the end product of Example 9 in 3 ml. acetone and 30 ml. of 1N HCl was heated to reflux for 2 hours. After cooling to room temperature, the mixture was concentrated in vacuo and the residue recrystallized twice from H2O/acetone/ether to give analytically pure end product as off-white prisms: mp 268°-269°.

1. additionA mixture of 1.05 g
2. temperatureto reflux for 2 hours
3. concentrationthe mixture was concentrated in vacuo
4. customthe residue recrystallized twice from H2O/acetone/ether
5. customto give analytically pure end product as off-white prisms