Dichloromethane → 1-(4-Chlorophenyl)-4-(4-isoquinolin-6-ylpyrazol-1-yl)butan-2-amine

HRID 662390Notes

Reaction equation

HRID 662390 reaction equation
[C:1]([O:2][C:3](=[O:4])[NH:7][CH:8]([CH2:9][c:10]1[cH:11][cH:12][c:13]([Cl:16])[cH:14][cH:15]1)[CH2:17][CH2:18][n:19]1[n:20][cH:21][c:22](-[c:24]2[cH:25][c:26]3[cH:27][cH:28][n:29][cH:30][c:31]3[cH:32][cH:33]2)[cH:23]1)([CH3:5])([CH3:6])[CH3:34].[Cl:42][CH2:43][Cl:44].[F:35][C:36]([F:37])([F:38])[C:39]([OH:40])=[O:41]>>[NH2:7][CH:8]([CH2:9][c:10]1[cH:11][cH:12][c:13]([Cl:16])[cH:14][cH:15]1)[CH2:17][CH2:18][n:19]1[n:20][cH:21][c:22](-[c:24]2[cH:25][c:26]3[cH:27][cH:28][n:29][cH:30][c:31]3[cH:32][cH:33]2)[cH:23]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 91607522tert-butyl N-[1-(4-chlorophenyl)-4-(4-isoquinolin-6-ylpyrazol-1-yl)butan-2-yl]carbamate

Product 1

HCID 683974361-(4-Chlorophenyl)-4-(4-isoquinolin-6-ylpyrazol-1-yl)butan-2-amine

Sources & evidence

ORD record
ord-bb15108593694bfb9ebf36025e6d5874
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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